产品货号：
Z10166
中文名称：
ADAMTS4抗体
英文名称：
Anti-ADAMTS4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ADAMTS4 Antibody |
| 指标别名 | ADAM TS 4;ADAM TS4;ADAMTS 2;ADAMTS 4;ADAMTS4;ADMP 1;Aggrecanase 1;KIAA0688 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | ADAMTS4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4 (813-837aa TPQDWLHRRAQILEILRRRPWAGRK),different from the related mouse sequence by five amino acids,and from the related rat sequence by six amino acids. |
| 实际分子量 | 90KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ADAMTS4,A disintegrin and metalloproteinase with thrombospondin motifs 4,is an enzyme that in humans is encoded by the ADAMTS4 gene.ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases.The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis.The enzyme encoded by this gene lacks a C-terminal TS motif.It is responsible for the degradation of aggrecan,a major proteoglycan of cartilage,and brevican,a brain-specific extracellular matrix protein.The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system,potentially,in the progression of glioma. |
| Uniprot ID | O75173 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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