产品货号:
Z10157
中文名称:
ABCC1抗体
英文名称:
Anti-ABCC1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ABCC1 Antibody |
指标别名 | ABC29;ABCC;ABCC1;Leukotriene C(4) transporter;LTC4 transporter;MRP;MRP1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | ABCC1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MRP1(1514-1531aa,LLQQRGLFYSMAKDAGLV),different from the related rat and mouse sequences by one amino acid. |
实际分子量 | 220KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra-and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance.This protein functions as a multispecific organic anion transporter,with oxidized glutatione,cysteinyl leukotrienes,and activated aflatoxin B1 as substrates.This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.Alternatively spliced variants of this gene have been described but their full-length nature is unknown. |
Uniprot ID | P33527 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | ATP-binding cassette,sub-family C(CFTR/MRP),member 1 |
蛋白名全称 | Multidrug resistance-associated protein 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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