产品货号：
Z10059
中文名称：
ABCG5抗体
英文名称：
Anti-ABCG5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ABCG5 Antibody |
| 指标别名 | ABCG5;Sterolin 1;STSL |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC-F,ICC,FCM |
| 基因名称 | ABCG5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human ABCG5(116-131aa NGRALRREQFQDCFSY). |
| 实际分子量 | 73KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ABCG5(Atp-binding cassette,subfamily g,member 5) also known as STEROLIN 1,is a protein that in humans is encoded by the ABCG5 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters.This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.The ABCG5 gene contains 13 exons and spans about 28kb.The ABCG5 gene is mapped on 2p21.It is expressed in a tissue-specific manner in the liver,colon,and intestine.This gene is tandemly arrayed on chromosome 2,in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis,and have been observed in patients with sitosterolemia.Small(2003) reviewed the role of ABC transporters in secretion of cholesterol from liver into bile,particularly the role of ABCG5/ABCG8.The ABCG5 and ABCG8 genes are an example of closely neighboring genes in a head-to-head orientation that,when mutated,cause the same phenotype. |
| Uniprot ID | Q9H222 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ATP-binding cassette,sub-family G(WHITE),member 5 |
| 蛋白名全称 | ATP-binding cassette sub-family G member 5 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry in fixed cells(ICC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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