产品货号:
Z10022
中文名称:
ABCA4抗体
英文名称:
Anti-ABCA4 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ABCA4 Antibody |
指标别名 | FFM;RMP;ABCR;RP19;STGD;ABC10;ARMD2;CORD3;STGD1;ABCA4 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ABCA4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ABCA4 (1890-1927aa FLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQR),different from the related mouse sequence by eight amino acids. |
实际分子量 | 256KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ABCA4 (ATP-Binding Cassette,Subfamily A,Member 4),also known as ABCR,is a protein which in humans is encoded by the ABCA4 gene.ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A (ABC1) found exclusively in multicellular eukaryotes.Using a whole genome radiation hybrid panel,this gene is mapped to 1p21-p13.And this gene is expressed exclusively in retina photoreceptor cells,indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane.Additionally,it is showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone,as well as rod,photoreceptors.The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration. |
Uniprot ID | P78363 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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