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产品目录

小鼠抗EPCAM抗体图片
产品货号:
YT711
中文名称:
小鼠抗EPCAM抗体
英文名称:
EPCAM Mouse Monoclonal Antibody
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
本品为来源于小鼠的抗EPCAM的单克隆抗体。
宿主:小鼠
克隆性:单克隆抗体
用途:WB,FC, IHC,ICC, IF
交叉反应性:人,小鼠
分子量:35KDa
推荐稀释比例:WB(1:1000-1:2000),IF(1:100-1:200),IHC(1:200-1:500),ICC(1:100-1:200),FC(1:100-1:200)

About this Antibody
Name EPCAM Mouse Monoclonal Antibody
Category Monoclonal antibody(mAb); Primary antibody
Isotype IgM
Purification ProL affinity purified
About the Immunogen
Immunogen This antibody is produced by immunizing mice with recombinant protein corresponding to a region of EpCAM .
Gene ID 4072
SwissProt P16422
Synonyms ESA; KSA; M4S1; MK-1; DIAR5; EGP-2;EGP40; KS1/4; MIC18; TROP1; TACSTD1; EPCAM
Category Adhesion/ECM
Background Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Mutations in EpCAM have also been associated with congenital tufting enteropathy which causes intractable diarrhea in newborn children .


注意事项:
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验,请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体,包括已经使用过的稀释抗体,请4℃保存。
2. 回收后重复使用的抗体,使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象,可以10,000g离心1-3分钟,取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况,则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得最佳的检测效果,请考虑使用上述检测专用的一抗稀释液。

储存条件:-20℃,有效期一年。
相关搜索:小鼠抗EPCAM抗体EPCAM Mouse Monoclonal Antibody
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