产品货号：
P11002
中文名称：
小鼠抗ERO1L单克隆抗体
英文名称：
ERO1L Antibody
产品规格：
50μL|100μL|150μL
发货周期：
1～3天
产品价格：
询价
宿主：小鼠
种属反应性：人、小鼠、大鼠
抗体类型：IgG2b
纯化方法：蛋白A纯化
浓度：1μg/μL
贮存液：PBS，50%甘油，含防腐剂
保存温度：-20℃
推荐应用及稀释比例：
蛋白别名：
ERO1 alpha
ERO1L
ERO1L alpha
ERO1 like (S.cerevisiae)
ERO1 like protein alpha
ERO1L
ERO1L相关说明：
ERO1L,also named as ERO1-alpha,is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.It acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange.It does not act as a direct oxidant of folding substrate,but relies on P4HB/PDI to transfer oxidizing equivalent.Associates with ERP44 but not with GRP54,demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins.Its reoxidation probably involves electron transfer to molecular oxygen via FAD.Glutathione may be required to regulate its activity in the endoplasmic reticulum.It may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell,thereby being a source of oxidative stress.It is required for the folding of immunoglobulin proteins.Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae,thereby playing a role in retrotranslocation of the toxin.
相关搜索：小鼠抗ERO1L单克隆抗体，ERO1A抗体，ERO1α抗体，ERO1L Antibody
种属反应性：人、小鼠、大鼠
抗体类型：IgG2b
纯化方法：蛋白A纯化
浓度：1μg/μL
贮存液：PBS，50%甘油，含防腐剂
保存温度：-20℃
推荐应用及稀释比例：
| 应用 | 说明 |
| WB | 1:5000～50000 |
| IHC | 1:500～2000 |
蛋白别名：
ERO1 alpha
ERO1L
ERO1L alpha
ERO1 like (S.cerevisiae)
ERO1 like protein alpha
ERO1L
ERO1L相关说明：
ERO1L,also named as ERO1-alpha,is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.It acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange.It does not act as a direct oxidant of folding substrate,but relies on P4HB/PDI to transfer oxidizing equivalent.Associates with ERP44 but not with GRP54,demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins.Its reoxidation probably involves electron transfer to molecular oxygen via FAD.Glutathione may be required to regulate its activity in the endoplasmic reticulum.It may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell,thereby being a source of oxidative stress.It is required for the folding of immunoglobulin proteins.Responsible for the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae,thereby playing a role in retrotranslocation of the toxin.
相关搜索：小鼠抗ERO1L单克隆抗体，ERO1A抗体，ERO1α抗体，ERO1L Antibody